## Abstract Partial tandem duplication (PTD) of the __MLL__ gene and internal tandem duplication (ITD) of the juxtamembrane region of the __FLT3__ receptor tyrosine kinase gene have been described in acute myeloid leukemia (AML) patients, preferentially in those with normal cytogenetics. These alte
β¦ LIBER β¦
Prognostic significance of FLT3 internal tandem duplication and tyrosine kinase domain mutations for acute myeloid leukemia: a meta-analysis
β Scribed by Yanada, M; Matsuo, K; Suzuki, T; Kiyoi, H; Naoe, T
- Book ID
- 110056360
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 160 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0887-6924
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## Abstract ## BACKGROUND The clinical relevance of mutations of the __FMS__βlike tyrosine kinase 3 (__FLT3__) gene in specific cytogenetic subgroups is not clear. The authors examined internal tandem duplication (ITD) and Asp835 mutations of __FLT3__ in patients with acute promyelocytic leukemia