A comprehensive analysis of human alloimmune cytotoxic T lymphocytes (CTLs) specific for the HLA-A2 antigen identified 11% of HLA-A2 positive cells as outliers. In total, 11 unrelated serologically indistinguishable, but distinguishable by cell-mediated lympholysis (CML) HLA-A2 positive outlier cell
The Serological Recognition of the Human MLC Determinants using a Modified Cytotoxicity Technique
β Scribed by J. J. VAN ROOD; A. VAN LEEUWEN; J. J. KEUNING; A. BLUSSE VAN OUD ALBLAS
- Book ID
- 115092516
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 444 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0001-2815
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Human alloimmune cytotoxic T cells, sensitized selectively against the HLA-A2 antigen, were tested on a panel of selected target cells. Five HLA-A2 positive outlier cells could be identified. These outlier cells were only weakly lysed by HLA-A2 specific CTLs, although they were serologically indisti
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