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The runx genes: gain or loss of function in cancer

โœ Scribed by Blyth, Karen; Cameron, Ewan R.; Neil, James C.


Book ID
109947381
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
386 KB
Volume
5
Category
Article
ISSN
1474-1776

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Gene duplication events are important sources of novel gene functions. However, more often than not, a duplicate gene may lose its function and become a pseudogene. What is the relative frequency of these two scenarios: functional divergence versus gene loss? Given that most non-neutral mutations ar