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Modularity in the gain and loss of genes: applications for function prediction

✍ Scribed by Thijs Ettema; John van der Oost; Martijn Huynen


Book ID
114173043
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
38 KB
Volume
17
Category
Article
ISSN
0168-9525

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As more studies are turning to bioinformatic prediction programs to assess the potential impact of amino acid substitutions, it is relevant to evaluate the prediction results these programs give in genes that have been well-characterized for Mendelian diseases. Eight genes responsible for neurodegen