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The role of tumor suppressor molecules in differentiation of murine kerationcytes, retinoblastoma susceptibility gene product and p53

โœ Scribed by P. A. Rehberger; F. Marks; K. H. Richter

Book ID
112784780
Publisher
Springer-Verlag
Year
1995
Tongue
English
Weight
141 KB
Volume
121
Category
Article
ISSN
1432-1335

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## Abstract The retinoblastoma protein (pRb105) is a true tumor suppressor as deregulation of the Rb pathway by either mutation of pRb105 itself or other proteins in the pathway, such as p16INK4a, occur in most cancers. This prototypical family member, along with the related p107 and p130, are invo