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The role of tissue factor/factor VIIa in the pathophysiology of acute thrombotic formation

โœ Scribed by Thomas J Girard; Nancy S Nicholson

Book ID
117786385
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
83 KB
Volume
1
Category
Article
ISSN
1471-4892

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Initiation of blood coagulation: the tis
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โœ Daniel Kirchhofer; Yale Nemerson ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 637 KB

Tissue factor (TF), a transmembrane glycoprotein, functions as an essential activator of the serine protease factor Vlla. This enzymatic complex is considered to be the principal initiator of in vivo coagulation. Recent studies emphasize the role of the TF/Vlla complex in a number of pathophysiologi