The role of the C-terminal region of olive latent virus 1 coat protein in host systemic infection
β Scribed by V. Pantaleo; F. Grieco; A. Di Franco; G. P. Martelli
- Publisher
- Springer Vienna
- Year
- 2006
- Tongue
- English
- Weight
- 545 KB
- Volume
- 151
- Category
- Article
- ISSN
- 1432-8798
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The 30-base pair (bp) deletion of the cytoplasmic carboxy-terminal domain of the latent membrane protein 1 (LMP-1) gene was analyzed in 37 frozen tissues from patients with Epstein-Barr virus (EBV)-related gastric cancer and 18 throat washings from healthy adults in southern Japan. The 30-bp deletio
## Abstract ## Background. The Cβterminal activation region 2 (CTAR2) of EpsteinβBarr virus latent membrane protein 1 is the major site that correlates with metastasisβrelated signaling pathway. The variation of CTAR2 sequence may affect the incidence of distant metastasis in patients with nasopha