## Epstein -Barr Virus (EBV) is implicated in the pathogenesis of endemic Burkitt's lymphoma (BL), B-cell lymphomas occuring under immunosuppression, nasopharyngeal carcinoma and Hodgkin's disease. Two distinct patterns of latent EBV gene expression occur in EBV-associated lymphomas. BLS typically
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Association of the Epstein-Barr virus latent membrane protein 1 with lipid rafts is mediated through its N-terminal region
β Scribed by S. Rothenberger; M. Rousseaux; H. Knecht; F.C. Bender; D.F. Legler; C. Bron
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 169 KB
- Volume
- 59
- Category
- Article
- ISSN
- 1420-682X
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A specific variant of Epstein-Barr virus (EBV) with a 30-bp deletion in the C-terminal region of the LMP1 gene has been found in some EBV-associated malignancies. To better understand the tumorigenic role of this LMP1 variant, we used PCR and sequencing to examine the LMP1 gene in 38 EBVassociated c