## Abstract Hepatitis C virus (HCV) infection may result in acute resolving or chronic infection. Patients that clear the infection have a more vigorous cellular immune response and an early humoral response to the hypervariable region 1 (HVR1) of the E2 envelope protein. To analyse further the pro
The serology of hepatitis C virus (HCV) infection: antibody crossreaction in the hypervariable region 1
β Scribed by M. da Silva Cardoso; K. Siemoneit; V. Nemecek; S. Epple; K. Koerner; B. Kubanek
- Publisher
- Springer Vienna
- Year
- 1995
- Tongue
- English
- Weight
- 870 KB
- Volume
- 140
- Category
- Article
- ISSN
- 1432-8798
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Hepatitis C virus (HCV) infection is characterized by persistence of liver inflammation that often leads to endβstage liver disease, although the mechanisms are not fully understood. A hyperβvariable region (HVR) has been reported in the E2/NS1 region of the HCV genome, in which strikin
## Abstract Recurrence of hepatitis C virus (HCV) infection after liver transplantation is almost universal and usually leads to chronic hepatitis with different degrees of severity. The pathogenic mechanisms underlying the variable outcome of HCV infection recurrence are not well defined, but rece
Antibodies directed to hypervariable region 1 (HVR1) of hepatitis C virus (HCV) have recently been shown to neutralize the corresponding HCV isolate in vitro. We analyzed the appearance of antibodies directed to HVR1 during the course of infection in a large group of patients who have been infected