The role of platelet-derived growth factor on human pluripotent progenitor (CFU-GEMM) growth in vitro
โ Scribed by Rita Michalevicz; Gillian E. Francis; Gillian M. Price; A.Victor Hoffbrand
- Book ID
- 113238394
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 406 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0145-2126
No coin nor oath required. For personal study only.
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An improved plasma clot culture system was developed for the culture of rat megakaryocyte colonies in vitro. Greater stimulation of megakaryocyte colony growth was provided when both serum and plasma were added to the culture medium than when plasma was added alone. Freeze-thawed extracts prepared f
Platelet-derived growth factor (PDGF) is a polypeptide found in a variety of tissues, including bone, where it could act as an autologous regulator of skeletal remodeling. Therefore, a recombinant B chain homodimer of human PDGF was studied for its effects on bone formation in cultured rat calvariae