An improved plasma clot culture system was developed for the culture of rat megakaryocyte colonies in vitro. Greater stimulation of megakaryocyte colony growth was provided when both serum and plasma were added to the culture medium than when plasma was added alone. Freeze-thawed extracts prepared f
Effects of human platelet-derived growth factor-AB on sarcoma growth in vitro and in vivo
✍ Scribed by Avni Abdiu; Sten Wingren; Sven-Erik Larsson; Åke Wasteson; Thomas M. Walz
- Book ID
- 117469446
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 407 KB
- Volume
- 141
- Category
- Article
- ISSN
- 0304-3835
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Platelet-derived growth factor (PDGF) is a 30 kDa protein consisting of disulfide-bonded dimers of Aand B-chains. PDGF receptors are of two types, a-and @-receptors, which are members of the protein-tyrosine kinase family of receptors. The receptors are activated by ligand-induced dimerization, wher