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The role of M1muscarinic cholinergic receptors in the discriminative stimulus properties ofN-desmethylclozapine and the atypical antipsychotic drug clozapine in rats

โœ Scribed by Adam J. Prus; Alan L. Pehrson; Scott D. Philibin; Jesse T. Wood; Sarah A. Vunck; Joseph H. Porter

Publisher
Springer
Year
2008
Tongue
English
Weight
195 KB
Volume
203
Category
Article
ISSN
0033-3158

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Role of D1 and D2 dopamine receptors in
Role of D1 and D2 dopamine receptors in the discriminative stimulus properties of the atypical antipsychotic clozapine in rats
โœ Joseph H. Porter; Heidi F. Villanueva; John A. Rosecrans ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 139 KB ๐Ÿ‘ 2 views

The purpose of the present study was to assess the role of dopamine D 1 and D 2 receptors in the discriminative stimulus properties of the atypical antipsychotic clozapine (CLZ). Two groups of rats were trained to discriminate either a moderate dose of clozapine (5.0 mg/kg) from vehicle or a high do