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Serotonin receptor mechanisms mediate the discriminative stimulus properties of the atypical antipsychotic clozapine in C57BL/6 mice

โœ Scribed by Scott D. Philibin; Adam J. Prus; Alan L. Pehrson; Joseph H. Porter


Publisher
Springer
Year
2005
Tongue
English
Weight
238 KB
Volume
180
Category
Article
ISSN
0033-3158

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The purpose of the present study was to assess the role of dopamine D 1 and D 2 receptors in the discriminative stimulus properties of the atypical antipsychotic clozapine (CLZ). Two groups of rats were trained to discriminate either a moderate dose of clozapine (5.0 mg/kg) from vehicle or a high do