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The role of hypoxia-inducible factors in renal fibrosis

โœ Scribed by Pan, Szu-Yu; Chang, Yu-Ting; Lin, Shuei-Liong

Book ID
121901174
Publisher
Chinese Electronic Periodical Services
Year
2013
Tongue
English
Weight
226 KB
Volume
112
Category
Article
ISSN
0929-6646

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Hypoxia-inducible factors (HIFs) are essential mediators of the cellular oxygen-signaling pathway. They are heterodimeric transcription factors consisting of an oxygen-sensitive alpha subunit (HIF-alpha) and a constitutive beta subunit (HIF-beta) that facilitate both oxygen delivery and adaptation t