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Oxygen-dependent diseases in the retina: Role of hypoxia-inducible factors

โœ Scribed by Olli Arjamaa; Mikko Nikinmaa

Book ID
116456412
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
268 KB
Volume
83
Category
Article
ISSN
0014-4835

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Hypoxia-inducible factors (HIFs) are essential mediators of the cellular oxygen-signaling pathway. They are heterodimeric transcription factors consisting of an oxygen-sensitive alpha subunit (HIF-alpha) and a constitutive beta subunit (HIF-beta) that facilitate both oxygen delivery and adaptation t