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A role for hypoxia and hypoxia-inducible transcription factors in tumor physiology

✍ Scribed by Acker, Till; Plate, Karl


Book ID
113016613
Publisher
Springer
Year
2002
Tongue
English
Weight
229 KB
Volume
80
Category
Article
ISSN
0946-2716

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Oxygen homeostasis represents an organizing principle for understanding metazoan evolution, development, physiology, and pathobiology. The hypoxia-inducible factors (HIFs) are transcriptional activators that function as master regulators of oxygen homeostasis in all metazoan species. Rapid progress