Hypoxia-Inducible Factors in Physiology
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Gregg L. Semenza
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Article
📅
2012
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Elsevier Science
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English
⚖ 417 KB
Oxygen homeostasis represents an organizing principle for understanding metazoan evolution, development, physiology, and pathobiology. The hypoxia-inducible factors (HIFs) are transcriptional activators that function as master regulators of oxygen homeostasis in all metazoan species. Rapid progress