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The role of hypoxia-inducible transcription factors in the hypoxic neonatal brain

✍ Scribed by Regina Trollmann; Max Gassmann


Book ID
113498766
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
380 KB
Volume
31
Category
Article
ISSN
0387-7604

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The role of hypoxia-inducible factors in
✍ Rankin, E B; Giaccia, A J πŸ“‚ Article πŸ“… 2008 πŸ› Nature Publishing Group 🌐 English βš– 209 KB

Hypoxia-inducible factors (HIFs) are essential mediators of the cellular oxygen-signaling pathway. They are heterodimeric transcription factors consisting of an oxygen-sensitive alpha subunit (HIF-alpha) and a constitutive beta subunit (HIF-beta) that facilitate both oxygen delivery and adaptation t