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The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism*1†2

✍ Scribed by Fisher, Michael B.; Paine, Mary F.; Strelevitz, Timothy J.; Wrighton, Steven A.

Book ID
111922625
Publisher
Informa plc
Year
2001
Tongue
English
Weight
321 KB
Volume
33
Category
Article
ISSN
0360-2532

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Stereoselective metabolism of propranolo
Stereoselective metabolism of propranolol glucuronidation by human UDP-glucuronosyltransferases 2B7 and 1A9
✍ Lushan Yu; Minrong Qian; Yao Liu; Tongwei Yao; Su Zeng 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 293 KB

## Abstract Stereoselective metabolism of propranolol side‐chain glucuronidation was studied for two recombinant human uridine diphosphate glucuronosyltransferases (UGTs), UGT1A9 and UGT2B7. The __S__‐ and __R__‐propranolol side‐chain glucuronides produced in the incubation mixtures were assayed si