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Metabolism and Renal Elimination of Gaboxadol in Humans: Role of UDP-Glucuronosyltransferases and Transporters

✍ Scribed by Xiao-Yan Chu; Yuexia Liang; Xiaoxin Cai; Karla Cuevas-Licea; Ronda K. Rippley; Kelem Kassahun; Magang Shou; Matthew P. Braun; George A. Doss; M. Reza Anari; Raymond Evers

Book ID
106493635
Publisher
Springer US
Year
2008
Tongue
English
Weight
211 KB
Volume
26
Category
Article
ISSN
0724-8741

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Xanthohumol (XN) is the principal prenylated flavonoid of the hop plant and has recently gained considerable interest due to its potential cancer-chemopreventive effects. However, the metabolism of XN has not yet been investigated in detail. Therefore, we studied the in vitro phase II metabolism of