Encyclopedia of Drug Metabolism and Interactions || Role and Clinical Consequences of Human UDP-Glucuronosyltransferases
β Scribed by Lyubimov, Alexander V.
- Book ID
- 120024509
- Publisher
- John Wiley & Sons, Inc.
- Year
- 2012
- Weight
- 739 KB
- Category
- Article
- ISBN
- 0470921927
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A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part comprehensively reviews the main enzyme systems in
## Abstract Stereoselective metabolism of propranolol sideβchain glucuronidation was studied for two recombinant human uridine diphosphate glucuronosyltransferases (UGTs), UGT1A9 and UGT2B7. The __S__β and __R__βpropranolol sideβchain glucuronides produced in the incubation mixtures were assayed si