## Abstract ## Background. Induction chemotherapy may contribute to decreased local and distant recurrences in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN) resectable for cure. ## Methods. Patients with previously untreated locally advanced stage IIIβIV (N0
The Role of Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma
β Scribed by Tobenna Nwizu; Maria Grazia Ghi; Ezra E.W. Cohen; Adriano Paccagnella
- Book ID
- 113900832
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 290 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1532-9461
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## Abstract Fiftyβone patients (32 previously untreated, 19 previously treated) with advanced squamous cell carcinoma of the head and neck received a single course of combination chemotherapy consisting of high dose __cis__βplatinum (DDP), bleomycin (Bleo), Β± high dose methotrexate (MTX). Thirtyβth
To determine the efficacy of adjuvant chemotherapy in patients with advanced head and neck squamous carcinoma, the National Cancer Insitute initiated a multi-institutional, prospective randomized trial termed the Head and Neck Contracts Program. Between 1978 and 1982,462 patients with resectable Sta