## Abstract We report on a family with comorbidity of Huntington's disease (HD) and idiopathic restless legs syndrome (RLS). All family members investigated and affected by RLS are also affected by HD, but not vice versa. The association of HD and RLS is discussed with respect to dopaminergic dysfu
The restless legs syndrome—A genetic view of the disease
✍ Scribed by Juliane Winkelmann; Karin Eckard; Bertram Müller-Myshok; Thomas Gasser; Claudia Trenkwalder
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 58 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1432-9123
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Dopaminergic agents are the best-studied agents and are considered first-line treatment of restless legs syndrome (RLS). Extensive data are available for levodopa, pramipexole, and ropinirole, which have approval for the indication RLS, and to a smaller extent for cabergoline, pergolide, and rotigot
## Abstract A large International Restless Legs Syndrome (RLS) Study Group has been formed. As its first task, the group has taken upon itself the role of definig the clinical features of the RLS. As minimal criteria for diagnosis, the group proposes the following four features: (a) desire to move