Genetics of restless legs syndrome: evidence for a hereditary disorder
โ Scribed by Eng-King Tan
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 253 KB
- Volume
- 254
- Category
- Article
- ISSN
- 0340-5354
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## Abstract Restless legs syndrome (RLS; MIM 102300) is a common neurological disorder characterized by dysesthesias and an urge to move the lower limbs. The symptoms predominantly occur at rest, in the evening, and improve with movement. There is a high familial aggregation but gene mutations have
## Abstract Only in the last three decades, the restless legs syndrome (RLS) has been examined in randomized controlled trials. The __Movement__ Disorder Society (MDS) commissioned a task force to perform an evidenceโbased review of the medical literature on treatment modalities used to manage pati
## Abstract We report on a family with comorbidity of Huntington's disease (HD) and idiopathic restless legs syndrome (RLS). All family members investigated and affected by RLS are also affected by HD, but not vice versa. The association of HD and RLS is discussed with respect to dopaminergic dysfu