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The relationship between MHC restricted and allospecific T cell recognition

✍ Scribed by Robert Lechler; Richard Batchelor; Giovanna Lombardi


Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
794 KB
Volume
29
Category
Article
ISSN
0165-2478

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Current models for T-cell recognition of foreign antigen depict the T-cell receptor as having a single antibody-like combining site which bindr a complex of MHC and antigen. An alternative hypothesis is presented here; it is proposed that the first domains of the MHC function as inverted V-like regi