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Why peptides? Their possible role in the evolution of MHC-restricted T-cell recognition

✍ Scribed by Zoltan A. Nagy; Paul V. Lehmann; Florenza Falcioni; Simone Muller; Adorini Luciano

Publisher: Elsevier Science
Year: 1989
Tongue: English
Weight: 872 KB
Volume: 10
Category: Article
ISSN: 0167-5699
DOI: 10.1016/0167-5699(89)90247-8

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## Abstract Direct intratumour injection of the disabled infectious single‐cycle–herpes simplex virus–encoding murine granulocyte/macrophage colony‐stimulating factor (DISC‐HSV–mGM‐CSF) into established colon carcinoma CT26 tumours induced complete tumour rejection in up to 70% of treated animals (