The relationship between cholinephosphate phosphatase (alkaline phosphatase) and phosphatidylcholine biosynthesis in HeLa cells
β Scribed by Harry B. Paddon; Dennis E. Vance
- Book ID
- 118309019
- Publisher
- Elsevier Science
- Year
- 1977
- Tongue
- English
- Weight
- 863 KB
- Volume
- 488
- Category
- Article
- ISSN
- 0005-2760
No coin nor oath required. For personal study only.
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## Abstract Parallel changes in the enzyme activities of Ca^2+^ ATPase and alkaline phosphatase were observed in HeLa cells. Both enzymes were inhibited to a similar degree by Lβphenylalanine, Lβtryptophan, and Lβleucine, while being relatively resistant to Lβhomoarginine. Exposure to heat (56Β°C, 6
Reduction in alkaline phosphatase activity was observed when HeLa S3 cells were grown in Puck's medium containing high concentrations of human serum. This effect was not seen with the enzyme of Chang liver 8A cells. The induction of increased alkaline phosphatase in HeLa S3 by prednisolone or by osm