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The Rearrangement Route to 3-Carboxy- and 3-Hydroxymethyl-2-azabicyclo[2.1.1]hexanes: 3,5-Methanoprolines

โœ Scribed by Krow, Grant R.; Lin, Guoliang; Yu, Fang


Book ID
126037180
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
145 KB
Volume
70
Category
Article
ISSN
0022-3263

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Additions to cyclobutenes: synthesis of
โœ Donald H. Aue; Hisashi lwahashi; Dale F. Shellhamer ๐Ÿ“‚ Article ๐Ÿ“… 1973 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 195 KB

As part of a study on additions to strained olefins and synthesis of strained nitrogen heterocycles, we have found that addition of methoxycsrbonylnitrene to 1,2dimethylcyclobutene, 2, and l-methylcyclobutene, 2, provides a convenient synthesis of the corresponding 5-azabicyclo[2.l.O]pentanes 2a and