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Second-Chance Rearrangement Route to Novel 5(6)-Syn,anti-difunctional 2-Azabicyclo[2.1.1]hexanes

โœ Scribed by Krow, Grant R.; Lin, Guoliang; Yu, Fang; Sonnet, Philip E.


Book ID
126249411
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
54 KB
Volume
5
Category
Article
ISSN
1523-7060

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## Novel Conversion of Perfluoro(2,6-dimethyl-1-azacyclohexene) to 3,3,4,4,5-Pentafluoro-2,6-diphenyl-2,6-bis (trifluoromethyl)-1azabicyclo[3.1.0]hexane. -Treatment of perfluoro-azacyclohexene (I) with 2 equiv. of phenyllithium (V) in a cyclohexane/Et 2 O mixture provides access to azabicyclohex