The reaction of pyrroles with trimethylhalosilanes-dialkyl sulfoxides
โ Scribed by Franco Bellesia; Franco Ghelfi; Romano Grandi; Ugo Maria Pagnoni; Adriano Pinetti
- Book ID
- 112130648
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1993
- Tongue
- English
- Weight
- 304 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0022-152X
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๐ SIMILAR VOLUMES
The reactions of p-O 2 NC 6 H 4 CH 2 Cl with (RO) 2 PO โซืโฌ in Me 2 SO with R โซืกโฌ Me, Et, Pr, Bu, CF 3 CH 2 , i-Pr or Ph involve the formation of p-O 2 NC 6 H 4 CH 2 P(O)(OR) 2 by S N 2 substitution followed by a further S RN 1 p-nitrobenzylation of p-O 2 NC 6 H 4 CH[P(O)(OR) 2 ] โซืโฌ and p-O 2 NC 6 H
The reversible formation of sulfodichloride intermediates (&,) has been proposed to explain the RlR2SO + 2HCl&lR2SC123 + Ii20 (Eq. 1) 1 s racemization of optically active sulfoxides by hydrogen chloride in organic solvents (Eq. 1). 1,2 Mislow' h8S suggested that the symmetrization of the sulfodic