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The preparation of α,β-acetylenic ketones by condensation of lithium acetylides with lactones

✍ Scribed by John C. Chabala; John E. Vincent

Book ID
104237169
Publisher
Elsevier Science
Year
1978
Tongue
French
Weight
217 KB
Volume
19
Category
Article
ISSN
0040-4039

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✦ Synopsis

We have been examining synthetic approaches to spiroketal rings of types 1 and 2, structural units common to a wide variety of natural products including steroid sapogenins,2 oligomycins, 3 milbemycins,4 and many polyether antibiotics, e.g., monensin5 and antibiotic

A231876

During the course of this work we discovered that 1 eq. of the lithium salt of the

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