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The reaction of trialkylstannylmethyllithium with α,β-epoxy ketones. A preparative method of β, γ-unsaturated ketones by homologation of α, gb-unsaturated ketones

✍ Scribed by Tadashi Sato; Toshihiro Kikuchi; Norio Sootome; Eigoro Murayama

Publisher
Elsevier Science
Year
1985
Tongue
French
Weight
224 KB
Volume
26
Category
Article
ISSN
0040-4039

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✦ Synopsis

a,@-Epoxy ketones 2_, upon treatment with two equivalents of trialkylstannylmethyllithium 1, afforded cyclopropanols 2 as a single product in acyclic system, and a mixture of cyclopropanols 2 and methylene 1,2-diols 2 in cyclic system. Under acidic conditions, the cyclopropanols gave p,y-unsaturated ketones 5 in good yields.

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