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The preparation of some dipeptides containing asparagine, aspartic acid, and glutamine

✍ Scribed by Leach, SJ; Lindley, H


Book ID
121219443
Publisher
Commonwealth Scientific and Industrial Research Organisation Publishing
Year
1954
Tongue
English
Weight
642 KB
Volume
7
Category
Article
ISSN
0004-9425

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Enantioselective Preparation of Ξ²2-Amino
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S)-b 2 -Homoamino acids with the side chains of Asp, Glu, Asn, and Gln have been prepared and suitably protected (N-Fmoc, CO 2 t Bu, CONHTrt) for solid-phase peptide syntheses. The key steps of the syntheses are: N-acylation of 5,5-diphenyl-4-isopropyl-1,3-oxazolidin-2-one (DIOZ) with succinic and g