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The peroxisome proliferator-activated receptor interacts with the retinoid X receptor in vivo

✍ Scribed by Miyata, Kenji S.; McCaw, Shannon E.; Marcus, Sandra L.; Rachubinski, Richard A.; Capone, John P.

Book ID: 122771918
Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 419 KB
Volume: 148
Category: Article
ISSN: 0378-1119
DOI: 10.1016/0378-1119(94)90707-2

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## Abstract The peroxisome proliferator‐activated receptor‐α (PPAR‐α) plays a key role in lipid metabolism and inflammation. Recently, we demonstrated that administration of the PPAR‐α agonists gemfibrozil and fenofibrate, inhibit the clinical signs of experimental autoimmune encephalomyelitis (EAE