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Retinoid X receptor and peroxisome proliferator-activated receptor activate an estrogen responsive gene independent of the estrogen receptor

✍ Scribed by Susan B Nuñez; Jeffrey A Medin; Olivier Braissant; Lawrence Kemp; Walter Wahli; Keiko Ozato; James H Segars

Book ID
117463655
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
670 KB
Volume
127
Category
Article
ISSN
0303-7207

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## Abstract The peroxisome proliferator‐activated receptor‐α (PPAR‐α) plays a key role in lipid metabolism and inflammation. Recently, we demonstrated that administration of the PPAR‐α agonists gemfibrozil and fenofibrate, inhibit the clinical signs of experimental autoimmune encephalomyelitis (EAE