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The Nm23-H1 metastasis suppressor as a translational target

✍ Scribed by Jean-Claude Marshall; Joshua Collins; Natascia Marino; Patricia Steeg

Book ID
116430338
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
112 KB
Volume
46
Category
Article
ISSN
0959-8049

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## Abstract __p53__, a tumor suppressor gene involved in the G1 cell cycle checkpoint, is also the most frequently mutated gene in human cancer. In addition, p53 modifies the ability of tumor cells to metastasize. The metastasis‐associated gene __Nm23‐H1__, which encodes an 18‐kDa nucleoside diphos