p53 is a regulator of the metastasis sup
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Shen-Liang Chen; Yi-Shin Wu; Hsin-Ying Shieh; Chun-Che Yen; Jiann-Jong Shen; Kwa
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Article
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2003
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John Wiley and Sons
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English
β 369 KB
## Abstract __p53__, a tumor suppressor gene involved in the G1 cell cycle checkpoint, is also the most frequently mutated gene in human cancer. In addition, p53 modifies the ability of tumor cells to metastasize. The metastasisβassociated gene __Nm23βH1__, which encodes an 18βkDa nucleoside diphos