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The metastasis suppressor Nm23 as a modulator of Ras/ERK signaling

✍ Scribed by Takács-Vellai, Krisztina


Book ID
125402829
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
360 KB
Volume
9
Category
Article
ISSN
1750-2187

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## Abstract __p53__, a tumor suppressor gene involved in the G1 cell cycle checkpoint, is also the most frequently mutated gene in human cancer. In addition, p53 modifies the ability of tumor cells to metastasize. The metastasis‐associated gene __Nm23‐H1__, which encodes an 18‐kDa nucleoside diphos