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The multiple-dosing pharmacokinetics of artemether, artesunate, and their metabolite dihydroartemisinin in rats

✍ Scribed by Xing, J.; Bai, K.H.; Liu, T.; Wang, R.L.; Zhang, L.F.; Zhang, S.Q.

Book ID
121316489
Publisher
Informa plc
Year
2010
Tongue
English
Weight
712 KB
Volume
41
Category
Article
ISSN
0049-8254

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## Abstract Recently, promising fasciocidal activities of artesunate and artemether were described in rats and sheep. Therefore, a liquid chromatography–tandem mass spectrometry (LC–MS/MS) method was developed to quantify artesunate, artemether and their metabolites dihydroartemisinin and dihydroar