Dose-independent pharmacokinetics of met
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Young H. Choi; Sang G. Kim; Myung G. Lee
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Article
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2006
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John Wiley and Sons
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English
β 151 KB
Pharmacokinetic parameters of metformin were evaluated after intravenous and oral administration (50, 100, and 200 mg/kg) in rats. The hepatic, gastric, and intestinal first-pass effects were also measured after intravenous, intraportal, intragastric, and intraduodenal administration (100 mg/kg) in