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Route-dependent stereoselective pharmacokinetics of tramadol and its active O-demethylated metabolite in rats

✍ Scribed by Ridhi Parasrampuria; Ragini Vuppugalla; Katherine Elliott; Reza Mehvar


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
214 KB
Volume
19
Category
Article
ISSN
0899-0042

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Enantiomeric separation of tramadol and
✍ M.A. Campanero; B. Calahorra; M. Valle; I.F. Troconiz; J. Honorato πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 131 KB πŸ‘ 2 views

A sensitive and stereoselective high-performance liquid chromatographic assay for the quantitative determination of the analgesic tramadol and Odemethyltramadol, an active metabolite, is described in this work. Ketamine was used as internal standard. The assay involved a single tert-butymethylether