Dose-independent pharmacokinetics of torasemide after intravenous and oral administration to rats
โ Scribed by Dae Y. Lee; Ji Y. Kim; Yu C. Kim; Jong W. Kwon; Won B. Kim; Myung G. Lee
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 111 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0142-2782
- DOI
- 10.1002/bdd.447
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๐ SIMILAR VOLUMES
The pharmacokinetics of the anticholinergic drug ethopropazine (ET) have been studied in the rat after intravenous (i.v.) and oral administration. After i.v. doses of 5 and 10 mg/kg ET HCl, mean +/- S.D. plasma AUC were 9836 +/- 2129 (n = 4 rats) and 13096 +/- 4186 ng h/mL (n = 5 rats), respectively
The pharmacokinetics of progesterone were characterized in ovariectomized female rats. Progesterone was administered intravenously at a dose of 500 pg kg-'. Serum progesterone concentrations were determined by radioimmunoassay. Serum concentrations of progesterone were best described by a two-compar