✦ LIBER ✦

Pharmacokinetics and dose proportionality of BMS-204352 after intravenous administration to dogs

✍ Scribed by Rajesh Krishna; Vinod R. Shah; Subbaro Mantha; Nimish N. Vachharajani; Nuggehally Srinivas

Publisher: John Wiley and Sons
Year: 2002
Tongue: English
Weight: 66 KB
Volume: 23
Category: Article
ISSN: 0142-2782
DOI: 10.1002/bdd.294

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Pharmacokinetics and dose proportionalit

Pharmacokinetics and dose proportionality of BMS-204352 after intraarterial administration to rats

✍ Rajesh Krishna; Vinod R. Shah; Nuggehally Srinivas 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 73 KB

BMS-204352 is a novel maxi-K channel opener that is being developed for the treatment for stroke. The current study was designed to evaluate the dose proportionality and pharmacokinetics of BMS-204352 in rats. In an open, parallel fashion, sixteen rats per gender received a single intraarterial dose

Dose-independent pharmacokinetics of tor

Dose-independent pharmacokinetics of torasemide after intravenous and oral administration to rats

✍ Dae Y. Lee; Ji Y. Kim; Yu C. Kim; Jong W. Kwon; Won B. Kim; Myung G. Lee 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 111 KB 👁 1 views

Effect of dose and input rate on the bra

Effect of dose and input rate on the brain penetration of BMS-204352 following intravenous administration to rats

✍ Rajesh Krishna; Holly Palme; Jianing Zeng; Nuggehally Srinivas 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 70 KB

Clinical pharmacokinetics of procaterol:

Clinical pharmacokinetics of procaterol: Dose proportionality after administration of single oral doses

✍ Dr Michael A. Eldon; Debbie S. Blake; Michael J. Coon; Gerald D. Nordblom; Allen 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 328 KB 👁 1 views

Procaterol is a potent, orally active &-agonist bronchodilator useful in the treatment of reversible bronchospastic disease. It is effective when administered as single or multiple (Q8H) 50 and 75pg doses. As part of the clinical development of procaterol, the pharmacokinetics and dose proportionali

Pharmacokinetics of fenvalerate after in

Pharmacokinetics of fenvalerate after intravenous administration to sheep

✍ Danielson, Terry J.; Golsteyn, Lorraine R.; Elder, James L. 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 475 KB 👁 2 views

The pharmacokinetics of total radioactivity and of intact fenvalerate were determined in sheep treated intravenously with radiolabelled or nonradiolabelled fenvalerate. Mean residence times (MRT) of total radioactivity and intact fenvalerate in plasma were 910 (f 75) and 39 ( f 3) min, while harmoni

Pharmacokinetics of deramciclane in dogs

Pharmacokinetics of deramciclane in dogs after single oral and intravenous dosing and multiple oral dosing

✍ Harri Kanerva; Hannele Huuskonen; Anneli Alhonen-Raatesalmi; Timo Nevalainen; Ar 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 204 KB 👁 2 views

The pharmacokinetics of a new serotonin 5-HT 2 antagonist, deramciclane, was studied. Single oral doses of 1, 3, 6 and 10 mg kg -1 and intravenous doses of 1, 3 and 6 mg kg -1 were administered in beagle dogs. Moreover, the steady state pharmacokinetics of 1, 3 and 6 mg kg -1 doses were studied. Der