The molecular basis of coeliac disease
β Scribed by C. S. Hourigan
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 59 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0372-8722
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Celiac disease is caused by inflammatory, gluten specific T cell responses in the small intestine. Invariably such responses are HLAβDQ2 or HLAβDQ8 restricted, providing an explanation for the strong association between celiac disease and these HLAβclass II alleles. It is now clear that
The pace of localization and characterization of genes affected in human genetic disorders is quickening. Many important genes were localized or characterized recently: genes for in cystic fibrosis, NF-2, Marfan's syndrome and xeroderma pigmentosum, to name a few. Also, in the past 15 months, the CF