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The membrane attack complex of complement and its precursor proteins lack phospholipase activity

✍ Scribed by Carl-Wilhelm Vogel; Andreas Plückthun; Eckhard R. Podack; Edward A. Dennis; Hans J. Müller-Eberhardb


Book ID
119089206
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
887 KB
Volume
20
Category
Article
ISSN
0161-5890

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## Abstract The membranolytic C5b‐9 complement membrane attack complex (MAC) is assembled after activation of either the classic or the alternative complement pathway. The quaternary configuration of the MAC macromolecule presents neoantigenic determinants not present on precursor molecules. Conseq