The structure and function of mammalian membrane-attack complex/perforin-like proteins
β Scribed by S. C. Kondos; T. Hatfaludi; I. Voskoboinik; J. A. Trapani; R. H. P. Law; J. C. Whisstock; M. A. Dunstone
- Book ID
- 110893276
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 928 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0001-2815
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Protectin (CD59) inhibits homologous complement-mediated cytolysis by preventing formation of the membrane attack complex at the point of insertion and polymerization of C9 into cell membranes. The present study investigated the expression and function of CD59 on human prostatic tumor cells in situ