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Formation of ion-conducting channels by the membrane attack complex proteins of complement

✍ Scribed by Shiver, J.W.; Dankert, J.R.; Esser, A.F.

Book ID
119409638
Publisher
Biophysical Society
Year
1991
Tongue
English
Weight
855 KB
Volume
60
Category
Article
ISSN
0006-3495

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Recent studies on the functional activities of the membrane attack complex of complement, C5b-9, are reviewed. A new speculative hypothesis has been advanced to account for the ability of complement to mediate lysis of various targets. This hypothesis has three major elements: 1) that the membrane a