𝔖 Bobbio Scriptorium
✦   LIBER   ✦

THE INK4a/ARF NETWORK IN TUMOUR SUPPRESSION

✍ Scribed by Sherr, Charles J.


Book ID
109776018
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
425 KB
Volume
2
Category
Article
ISSN
1471-0072

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Tumor suppression by Ink4a–Arf: progress
✍ Scott W Lowe; Charles J Sherr πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 English βš– 138 KB

The two products of the Ink4aΒ±Arf locus, p16 Ink4a and p19 Arf (p14 ARF in humans), are potent tumor suppressors that regulate the activities of the retinoblastoma protein and the p53 transcription factor. These proteins form part of a signaling network that is disrupted in most, if not all, cancer