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The influence of raphe lesions on the effect of morphine on nociception and cortical ACh output

✍ Scribed by L. Garau; M.L. Mulas; G. Pepeu

Book ID
118953458
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
326 KB
Volume
14
Category
Article
ISSN
0028-3908

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πŸ“œ SIMILAR VOLUMES

Effects of medial raphe and raphe magnus
Effects of medial raphe and raphe magnus lesions on the analgesic activity of morphine and methadone
✍ William T. Chance; Glenn M. Krynock; John A. Rosecrans πŸ“‚ Article πŸ“… 1978 πŸ› Springer 🌐 English βš– 523 KB

The effects of lesions of the raphe nuclei on opiate-induced antinociception and brain serotonin (5-HT) levels were investigated. Lesions of the medial raphe nucleus effectively antagonized the analgesic effects of morphine, but not methadone, and lowered brain 5-HT. The decrement in analgesic activ