DNA methylation in mammals is required for embryonic development, X chromosome inactivation and imprinting. Previous studies have shown that methylation patterns become abnormal in malignant cells and may contribute to tumorigenesis by improper de novo methylation and silencing of the promoters for
โฆ LIBER โฆ
The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors
โ Scribed by Robertson, K. D.; Uzvolgyi, E.; Liang, G.; Talmadge, C.; Sumegi, J.; Gonzales, F. A.; Jones, P. A.
- Book ID
- 125512350
- Publisher
- Oxford University Press
- Year
- 1999
- Tongue
- English
- Weight
- 356 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0305-1048
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